Effect of cavendish green banana flour " The Mediterranean "on the improvement of metabolic dysfunctions in diabetic Wistar rats

Abstract

Green bananas, a rich source of bioactive compounds essential for human health. The objective of this study was to examine the beneficial effects of Cavendish Green Banana Flour "The Mediterranean" consumption on diabetic Wistar rats. The experimental rats were randomly divided into 3 groups: the negative control group (NCG) received a standard diet (SD), the positive control group (PCG) received a high-fat diet (HFD), and the green banana group (GBG) received a HFD enriched with green banana flour (GBF). The diabetic animal model was established through a 10-week HFD followed by a low dose (35 mg/kg) of streptozotocin (STZ). The experimental results after the 4th week revealed that the rats in the GBG began to adjust their daily food intake (both solid and liquid). Their weight gain was significantly inhibited when compared to the PCG. Blood glucose levels decreased, and serum levels demonstrated considerable improvement. Organ weights and histological sections showed significant improvements in the pancreas, liver, kidneys, and testes, along with a notable reduction in body fat mass. The findings of this study demonstrate that green banana flour "The Mediterranean" has facilitated the improvement of blood glucose levels and the complications associated with metabolic disorders due to diabetes in rats. This study supports the use of "The Mediterranean" green banana flour as a functional food for managing blood glucose and metabolic disorders. It provides a natural dietary alternative to improve the health outcomes and quality of life for diabetic patients.