Epidemiological pattern and regional characteristics of congenital malformations in the Turkistan region

Abstract

This article explores the epidemiological pattern and regional characteristics of congenital malformations (CMs) in the Turkistan region. The study is based on data collected from regional perinatal centers and healthcare institutions from 2020 to 2024. During this period, 53,169 pregnancies were registered, and congenital malformations were diagnosed in 848 cases (1.6%). Year-by-year analysis revealed a consistent increase in CM prevalence: 0.8% in 2020, rising to 2.4% in 2024. The dynamics of absolute and relative growth rates were assessed, and regression modeling was applied to forecast future trends. Projections indicate that the number of CM cases could reach 310 in 2025 and 357 in 2026. The findings underscore the need to monitor contributing factors, enhance preventive measures, and improve screening programs. The resulting data serve as a critical foundation for planning and optimizing perinatal care in the Turkistan region.